Piperidine → 3-piperidin-1-ylbenzonitrile

HRID 365731Notes

Reaction equation

F[C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[C:5]#[N:6].[NH:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1>>[N:10]1([C:2]2[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=2)[C:5]#[N:6])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1

Participants

Reactant 2

HCID 8082Piperidine

HCID 678803-Fluorobenzonitrile

Product 1

HCID 70605663-piperidin-1-ylbenzonitrile

Procedure

According to a similar manner to that in Reference Example 17, the title compound was synthesized from 3-fluorobenzonitrile and piperidine.

Sources & evidence

ORD record: ord-5184a0893b5a47e8a32eabdc116304b7
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

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