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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 365735Generated: October 31, 2026

4-Fluorobenzonitrile → 4-(4-Methylpiperazin-1-yl)benzonitrile

https://huagongshe.com/reaction/365735

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzonitrileHCID 14517—
Reactant1-MethylpiperazineHCID 53167—
Product4-(4-Methylpiperazin-1-yl)benzonitrileHCID 763205—

Reaction Steps

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 4-fluorobenzonitrile and 1-methylpiperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06127541
Source datasetuspto-grants-2000_10
ORD IDord-53a89450a2d440ca82db801a15824113
Source noteuspto-grants-2000_10