3-Fluorobenzonitrile → HCID 11414238, compound

HRID 365746Notes

Reaction equation

HRID 365746 reaction equation
F[C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[C:5]#[N:6].[NH:10]1[CH2:20][CH2:19][CH:13]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH2:12][CH2:11]1>>[CH2:17]([O:16][C:14]([CH:13]1[CH2:19][CH2:20][N:10]([C:2]2[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=2)[C:5]#[N:6])[CH2:11][CH2:12]1)=[O:15])[CH3:18]

Participants

3

Reactant 2

HCID 678803-FluorobenzonitrileHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 11414238HCID 11414238, compound

Procedure

According to a similar manner to that in Reference Example 17, the title compound was synthesized from 3-fluorobenzonitrile and ethyl isonipecotate.

Sources & evidence

ORD record
ord-93975293d17d43ff9c3ab31c56adfbf8
Source dataset
uspto-grants-2000_10
Patent number
US06127541

Reaction notes

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