Furfurylamine → 2-[(furan-2-ylmethyl)amino]benzonitrile

HRID 365757Notes

Reaction equation

F[C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[NH2:10][CH2:11][C:12]1[O:13][CH:14]=[CH:15][CH:16]=1>>[O:13]1[CH:14]=[CH:15][CH:16]=[C:12]1[CH2:11][NH:10][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

Participants

Reactant 2

HCID 3438Furfurylamine

HCID 678552-Fluorobenzonitrile

Product 1

HCID 232931212-[(furan-2-ylmethyl)amino]benzonitrile

Procedure

According to a similar manner to that in Reference Example 12, the title compound was synthesized from 2-fluorobenzonitrile and 2-(aminomethyl)furan.

Sources & evidence

ORD record: ord-2f26827e270c46e8952941f2677044d7
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06127541

Reaction notes

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