HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → (3-Bromo-6-hydroxy-2-methylphenyl)(2,3,4-trimethoxy-6-methylphenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Acetoxy-5-bromo-6,6'-dimethyl-2', 3', 4'-trimethoxy-benzophenone | HCID 10906251 | — |
| Solvent | Water | HCID 962 | — |
| Product | (3-Bromo-6-hydroxy-2-methylphenyl)(2,3,4-trimethoxy-6-methylphenyl)methanone | HCID 10938097 | — |
Reaction Steps
A mixture of 1D (0.7 g, 1.6 mmol), potassium carbonate (0.7 g), methanol (10 ml) and water (5 ml) is stirred at room temperature for 20 hours. The reaction mixture is poured into water and extracted with diisopropylether. The organic phase is separated and concentrated. The pure product is obtained as a yellow solid, 0.48 g (75.9%), mp. 119-120° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06127570 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-ee76843728674c7b8b3741362ba4a957 |
| Source note | uspto-grants-2000_10 |