HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178462151, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1,3-Bis(benzyloxycarbonyl)-2-methylisothiourea | HCID 4664213 | — |
| Reactant | (R)-N2-(Diphenylacetyl)-(S)-N-(1-phenylethyl)ornithine amide hydrochloride | HCID 131722046 | — |
| Product | HCID 178462151 | HCID 178462151 | 116.1% |
Reaction Steps
Prepared according to the method described in Example 4(f) above from (R)-N2 -(diphenylacetyl)-(S)-N-(1-phenylethyl)ornithine amide hydrochloride (0.50 g; 1.0 mmol; from step (c) above), N,N'-bis(Cbz)-S-methyliso-thiourea (0.40 g; 1.1 mmol) of and DiPEA (0.3 mL; 1.6 mmol), yielding 0.59 g (74%) of sub-title compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06127414 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-9cd505c89a99417f82fba00a5e190e7d |
| Source note | uspto-grants-2000_10 |