Sodium → HCID 23289704, compound

HRID 366371Notes

Reaction equation

HRID 366371 reaction equation
[F:1][C:2]1[CH:31]=[CH:30][C:5]([CH2:6][NH:7][C:8]2[C:9]3[C:25]4[CH2:26]CCC[C:24]=4[S:23][C:10]=3[N:11]=[C:12]([N:14]3[CH2:19][CH2:18][CH:17]([C:20]([OH:22])=[O:21])[CH2:16][CH2:15]3)[N:13]=2)=[CH:4][CH:3]=1.[Na]>>[CH3:26][C:25]1[C:9]2[C:8]([NH:7][CH2:6][C:5]3[CH:30]=[CH:31][C:2]([F:1])=[CH:3][CH:4]=3)=[N:13][C:12]([N:14]3[CH2:15][CH2:16][CH:17]([C:20]([OH:22])=[O:21])[CH2:18][CH2:19]3)=[N:11][C:10]=2[S:23][CH:24]=1

Participants

3

Reactant 2

HCID 5360545SodiumHCID 23289415HCID 23289415, compound

Product 1

HCID 23289704HCID 23289704, compound

Procedure

1-[5,6,7,8-tetrahydro-4-(4-fluorobenzylamino)-[1]-benzothieno-[2,3-d]-pyrimidin-2-yl]-piperidine-4-carboxylic acid, sodium salt, m.p. 279°;

Sources & evidence

ORD record
ord-8c7035a042f244108cb11e82421c039d
Source dataset
uspto-grants-2000_10
Patent number
US06130223

Reaction notes

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