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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 366379Generated: November 1, 2026

Boron trifluoride etherate → 6,7-Dihydro-5h-benzo[6,7]cyclohepta[1,2-b]quinolin-8-amine

https://huagongshe.com/reaction/366379

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoron trifluoride etherateHCID 8000—
ReactantBenzosuberoneHCID 70003—
Reactant2-AminobenzonitrileHCID 72913—
Product6,7-Dihydro-5h-benzo[6,7]cyclohepta[1,2-b]quinolin-8-amineHCID 402666—

Reaction Steps

2-amino-1-cyano-benzene (2.0 g, 16.9 mmol), 1-benzosuberone (6, 7, 8, 9-tetrahydrobenzocyclohepten-5-one) (3.0 g, 18.7 mmol) and boron trifluoride diethyl etherate(1M, 2.6 ml, 18.7 mmol) were treated according to the general procedure described herein to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06130228
Source datasetuspto-grants-2000_10
ORD IDord-d1c7110dad284227a64f47d1282aca0a
Source noteuspto-grants-2000_10