HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)piperazine → HCID 23289234, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)piperazine | HCID 2735936 | — |
| Reactant | Dioxane toluene | HCID 21840791 | — |
| Reactant | 2-Methyl-7-(7-oxa-bicyclo[4.1.0]hept-2-yloxy)-benzothiazole | HCID 23289293 | — |
| Reactant | 4-Bromo-2-oxa-bicyclo[4.1.0]heptane | HCID 23289331 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23289234 | HCID 23289234 | — |
| Product | 2-Methyl-7-(7-oxa-bicyclo[4.1.0]hept-2-yloxy)-benzothiazole | HCID 23289293 | — |
Reaction Steps
The title compound was prepared according to Method A from 2-methyl-7-(7-oxa-bicyclo[4.1.0]hept-2-yloxy)-benzothiazole and 1-(10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5-yl)piperazine with dioxane/toluene (2:1) as the solvent. mp 207° C. (decomposition); LSIMS m/z 540. The 2-methyl-7-(7-oxa-bicyclo[4.1.0]hept-2-yloxy)-benzothiazole was prepared according to Method IV using THF as the solvent and 4-bromo-2-oxa-bicyclo[4.1.0]heptane as the alkylating agent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06130217 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-67ee121c137b4d01a6ddf9c39fb83777 |
| Source note | uspto-grants-2000_10 |