HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 3-(5-Methyl-1,2,4-oxadiazol-3-yl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | N,3-dihydroxybenzenecarboximidamide | HCID 54381771 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 3-(5-Methyl-1,2,4-oxadiazol-3-yl)phenol | HCID 12042519 | — |
Reaction Steps
3-(5-Methyl-[1,2,4]oxadiazol-3-yl)-phenol was prepared using 3-hydroxybenzamidoxime (1 g, 6.6 mM) and acetyl chloride (0.52 g, 6.7 mM) in pyridine (4 mL) according to Preparation 62 to provide 0.66 g of a white powder; m.p., 87-89° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06130217 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-52fd1baa4a134488b0659cbab78f36d9 |
| Source note | uspto-grants-2000_10 |