2-Bromopyridine → HCID 23289237, compound

Participants

Reaction Steps

3-Aminophenol (3.0 g, 27.5 mM) and 2-bromopyridine (4.34 g, 27.5 mM) were combined in acetic acid (15 mL) and heated for about 18 hours. The mixture was concentrated in vacuo and placed on a column of silica gel (150 g). The product was eluted with 3% methanol/methylene chloride to provide 1.2 g of an off white solid.

Provenance & Evidence