HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 22448959, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 6-Hydroxy-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one | HCID 9942290 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 22448959 | HCID 22448959 | 87% |
Reaction Steps
A suspension of 1,3,4,5-tetrahydro-6-hydroxy-2H-1-benzazepin-2-one (500 mg, 2.82 mmol) in 2.5 mL each of pyridine and acetic acid was stirred at room temperature. Excess reagents were removed under reduced pressure and the residue was triturated with CH2Cl2 to give 540 mg (87%) of 1,3,4,5-tetrahydro-6-acetoxy-2H-1-benzazepin-2-one; MS 219.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06130217 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-70c2dc89be7249f8a3520f32da86a2e0 |
| Source note | uspto-grants-2000_10 |