HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 23289323, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) | HCID 2735153 | — |
| Reactant | HCID 23289285 | HCID 23289285 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 23289323 | HCID 23289323 | 91.8% |
Reaction Steps
To a solution of 1,3,4,5-tetrahydro-6-acetoxy-2H-1-benzazepin-2-thione (235 mg, 1.0 mmol) in 25 mL of CH2Cl2 was added at 0° 295 mg (2.0 mmol) of trimethyloxonium tetrafluoroborate. After stirring at room temperature for about 30 min. water was added and the CH2Cl2 layer was separated. Drying over Na2SO4 and removal of the solvent gave 229 mg of 4,5-dihydro-6-acetoxy-2-methylthio-3H-benzazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06130217 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-3b8f0b3662d84939ba864cec54953c2d |
| Source note | uspto-grants-2000_10 |