Propargyl bromide → HCID 86755938, compound

HRID 366843Notes

Reaction equation

HRID 366843 reaction equation

[CH2:1](Br)[C:2]#[CH:3].N12CCCN=C1CCCCC2.[C@@H:16]1([N:25]2[C:34]3[N:33]=[CH:32][N:31]=[C:29]([OH:30])[C:28]=3[N:27]=[CH:26]2)[O:24][C@H:21]([CH2:22][OH:23])[C@@H:19]([OH:20])[C@H:17]1[OH:18]>>[CH2:1]([N:31]1[CH:32]=[N:33][C:34]2[N:25]([C@@H:16]3[O:24][C@H:21]([CH2:22][OH:23])[C@@H:19]([OH:20])[C@H:17]3[OH:18])[CH:26]=[N:27][C:28]=2[C:29]1=[O:30])[C:2]#[CH:3]

Participants

4

Reactant 3

HCID 7842Propargyl bromide

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-ene

HCID 178521066(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-hydroxypurin-9-yl)oxolane-3,4-diol

Product 1

HCID 86755938HCID 86755938, compound

Procedure

reacting propargyl bromide, 1,8-diazabicyclo[5.4.0]undec-7-ene, and inosine to produce 1-propargylinosine;

Sources & evidence

ORD record: ord-243fce2a400343ff840faa4fdd92f753
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06130324

Reaction notes

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