HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → 2-Decylthio-3-hydroxynorbornane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 1-Decanethiol | HCID 8917 | — |
| Reactant | exo-2,3-Epoxynorbornane | HCID 18463 | — |
| Reactant | Phosphoric triamide, tris[tris(dimethylamino)phosphoranylidene]- | HCID 9829709 | — |
| Solvent | Hexamethylphosphorous triamide | HCID 15355 | — |
| Product | 2-Decylthio-3-hydroxynorbornane | HCID 10221481 | 95% |
Reaction Steps
A reaction was conducted as described in Example 1 except that tris[tris(dimethylamino)phosphoranylidene-amino]phosphine oxide was replaced with the same molar amount of a partially hydrated tris[tris(dimethylamino)phosphoranylidene-amino]phosphine oxide, [(Me2N)3P=N]3P=O.0.29H2O, phenol was replaced with the same molar amount of decanethiol and PGE was replaced with 2,3-epoxynorbornane. Desired 2-decylthio-3-hydroxynorbornane was formed in an analytical yield of 95% and isolated in a yield of 90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06130346 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-307063b2ab434fabb0a5c3ee1233789e |
| Source note | uspto-grants-2000_10 |