Benzoic Acid → HCID 23290241, compound

HRID 366920Notes

Reaction equation

HRID 366920 reaction equation
C(O)(=O)C1C=CC=CC=1.[CH3:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=1.[O:19]1[CH:21]2[CH2:22][CH:23]([O:28][CH3:29])[CH:24]([O:26][CH3:27])[CH2:25][CH:20]12>>[CH3:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH:20]2[CH2:25][CH:24]([O:26][CH3:27])[CH:23]([O:28][CH3:29])[CH2:22][CH:21]2[OH:19])=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 243Benzoic AcidHCID 90154-MethoxyphenolHCID 14673789HCID 14673789, compound

Product 1

HCID 23290241HCID 23290241, compoundYield 96%

Procedure

A reaction was conducted as described in Example 6 except that benzoic acid and PGE were replaced with the same molar amounts of 4-methoxyphenol and 1,2-epoxy-4,5-dimethoxycyclohexane. Desired 2-(4-methoxyphenoxy)-4,5-dimethoxycyclohexanol was formed in analytical yield of 96% and isolated in a yield of 92%.

Sources & evidence

ORD record
ord-fd38c154eb7442c085f6341d7f1d3b92
Source dataset
uspto-grants-2000_10
Patent number
US06130346

Reaction notes

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