Cesium carbonate → HCID 23287555, compound

HRID 367009Notes

Reaction equation

HRID 367009 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([OH:12])=[C:6]([O:13][CH3:14])[CH:5]=1)([O-:3])=[O:2].Cl[CH2:16][CH2:17][N:18]1[CH2:22][CH2:21][CH2:20][CH2:19]1.C(=O)([O-])[O-].[Cs+].[Cs+]>>[N+:1]([C:4]1[CH:5]=[C:6]([O:13][CH3:14])[C:7]([O:12][CH2:16][CH2:17][N:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)=[C:8]([O:10][CH3:11])[CH:9]=1)([O-:3])=[O:2]

Participants

4

Reactant 3

HCID 10796Cesium carbonateHCID 816691-(2-Chloroethyl)pyrrolidineHCID 106794894-Nitrosyringol

Product 1

HCID 23287555HCID 23287555, compound

Procedure

1-[2-(4-nitro-2,6-dimethoxyphenoxy)ethyl]pyrrolidine was prepared from 4-nitro-2,6-dimethoxyphenol [R F Collins and M Davis, J. Chem. Soc. 1863, (1961)] (0.4 g, 2.39 mmol), 1-(2-chloroethyl)pyrrolidine (612 mg, 0.36 mmol) and caesium carbonate (2.3 g, 0.72 mmol) to give the desired product as a brown oil (232 mg). MS (ES+) 297 (MH+).

Sources & evidence

ORD record
ord-43ffdb32ffb5433fa8d3dc81576035ea
Source dataset
uspto-grants-2000_10
Patent number
US06133257

Reaction notes

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