Methyl iodide → HCID 12216083, compound

HRID 367144Notes

Reaction equation

HRID 367144 reaction equation
[NH:1]([C:8]1[S:9][C:10]2[N:18]=[CH:17][CH:16]=[CH:15][C:11]=2[C:12](=[O:14])[N:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].[Li+].[CH3:21]I>>[CH3:21][N:13]1[C:12](=[O:14])[C:11]2[CH:15]=[CH:16][CH:17]=[N:18][C:10]=2[S:9][C:8]1=[N:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 62714Lithium hydrideHCID 122160784H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-(phenylamino)-

Product 1

HCID 12216083HCID 12216083, compound

Procedure

The reaction procedure of Example 11 was followed except that 255 mg of 2-anilino-4H-pyrido[3,2-e]-1,3-thiazin-4-one, 9 mg of lithium hydride and 0.063 ml of methyl iodide were used. As a result, 113 mg of 3-methyl-2-phenylimino-2,3-dihydro-4H-pyrido[3,2-e]-1,3-thiazin-4-one was obtained.

Workup

  1. customThe reaction procedure of Example 11

Sources & evidence

ORD record
ord-285b4f74afa04553a1a9c82032de3d2f
Source dataset
uspto-grants-2000_10
Patent number
US06133258

Reaction notes

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