Potassium Bromide → HCID 23287918, compound

HRID 367269Notes

Reaction equation

[CH2:1]([N:5]1[C:10](=[O:11])[C:9]([N+:12]([O-])=O)=[C:8]([CH3:15])[N:7]([CH2:16][CH2:17][CH:18]([CH3:20])[CH3:19])[C:6]1=[O:21])[CH2:2][CH2:3][CH3:4].[K+].[Br-]>>[NH2:12][C:9]1[C:10](=[O:11])[N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[C:6](=[O:21])[N:7]([CH2:16][CH2:17][CH:18]([CH3:19])[CH3:20])[C:8]=1[CH3:15]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 23287916HCID 23287916, compound

Product 1

HCID 23287918HCID 23287918, compoundYield 100%

Procedure

The title compound was prepared according to the procedure of example 18, step 3 except that 3-butyl-6-methyl-1-(3-methyl-butyl)-5-nitro-1H-pyrimidine-2,4-dione was used in place of 1-butyl-3,6-dimethyl-5-nitro-1H-pyrimidine-2,4-dione. Yield: 100%; mp: 68-70° C.; 1H NMR (300 MHz, CDCl3); δ 0.91-0.98 (m, 6H), 1.25 (s, 3H), 1.32-1.40 (m, 2H), 1.48-1.80 (m, 5H), 2.15 (s, 3H), 3.21 (m, 2H) 3.67-3.83 (m, 2H), 3.88-3.96 (m, 2H); IR (KBr, cm-1): 3435w, 3414w, 2959w, 2930w, 2869m, 1683s, 1644s, 1589m,1488m, 1359m; MS (ES) m/z (relative intensity): 268 (M+ +H). Anal. Calcd. for C14H25N3O2 : C, 62.89; H, 9.42, N, 15.72. Found: C, 62.76; H, 9.23; N, 15.59.

Sources & evidence

ORD record: ord-4bb21fbc03174f799ac9b83826e08a73
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06133273

Reaction notes

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