HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 23288077, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 3061874 | HCID 3061874 | — |
| Reactant | 5-Chloro-3-(1-methyl-4-piperidinyl)indole | HCID 11413992 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Product | HCID 23288077 | HCID 23288077 | — |
Reaction Steps
5-Chloro-3-(1-methyl-4-piperidinyl)indole: (0.89 g, 88%); from 5-chloro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)indole (Example 4d, 1.0 g, 4 mmol) and 5% Pt/C (0.78 g, 0.2 mmol) in methanol under H2 ; mp 192-4° C.; HRMS-FAB+ for C14H17N2Cl calculated MH+: 249.11584, found: 249.11529.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133287 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-186a5ecc9b764dbf8fe98f433f141ffd |
| Source note | uspto-grants-2000_10 |