Pyrazole → 2-(Pyrazol-1-yl)-6-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine

HRID 367580Notes

Reaction equation

HRID 367580 reaction equation
[NH:1]1[CH:5]=[CH:4][CH:3]=[N:2]1.Cl[C:7]1[N:8]=[C:9]([NH:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:10]2[CH:15]=[C:14]([CH3:16])[S:13][C:11]=2[N:12]=1>>[N:1]1([C:7]2[N:8]=[C:9]([NH:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:10]3[CH:15]=[C:14]([CH3:16])[S:13][C:11]=3[N:12]=2)[CH:5]=[CH:4][CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 1048PyrazoleHCID 184601702-Chloro-6-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine

Product 1

HCID 184604232-(Pyrazol-1-yl)-6-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine

Procedure

Following the procedure of Example 97, the reaction of pyrazole with 2-chloro-6-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine gives 2-(pyrazol-1-yl)-6-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-1bef25090b08491db8873ba7d4f5d2f5
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

Loading…