HRID3681

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11776

Triphenylphosphine

C18H15P

结构：CCOC(=O)C(C)(C)CCCOc1ccc(OCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.[Br-]

HCID18935261

未命名化合物

HCID18935281

未命名化合物

PRODUCTS

生成物

HCID11776

Triphenylphosphine

C18H15P

HCID24408

Bromine

Br2

HCID18935269

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6342

Acetonitrile

C2H3N

2 次

PROCEDURE

实验过程

The 3-[4-(4,4-dimethyl-4-ethoxycarbonylbutoxy)phenoxy]propyltriphenylphosphonium bromide used as starting material was prepared by reacting triphenylphosphine in acetonitrile, at reflux, with ethyl 2,2-dimethyl-5-[4-(3-bromopropyloxy)phenoxy]pentanoate, itself obtained from ethyl 5-[4-(3-hydroxypropyloxy)phenoxy]pentanoate and bromine in acetonitrile in the presence of triphenylphosphine.

WORKUP

后处理

customwas prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1ed77840c3734a39844b39f7948bc2ab
来源数据集: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05734077
来源说明: uspto-grants-1998_03

反应 SMILES

[Br-:1].C[C:3](C)([C:37]([O:39][CH2:40][CH3:41])=[O:38])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[CH:36]=[CH:35][C:11]([O:12][CH2:13][CH2:14][CH2:15][P+:16]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:10][CH:9]=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.CC(C)(CCCOC1C=CC(OCCC[Br:83])=CC=1)C(OCC)=[O:65]>C(#N)C>[OH:65][CH2:15][CH2:14][CH2:13][O:12][C:11]1[CH:35]=[CH:36][C:8]([O:7][CH2:6][CH2:5][CH2:4][CH2:3][C:37]([O:39][CH2:40][CH3:41])=[O:38])=[CH:9][CH:10]=1.[Br:1][Br:83].[C:29]1([P:16]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=1