Thionyl Chloride → HCID 19936198, compound

HRID 36814Notes

Reaction equation

HRID 36814 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([OH:23])=O)=[CH:11][CH:10]=2)=[CH:5][CH:4]=1)#[N:2].S(Cl)([Cl:26])=O>CN(C)C=O.C1(C)C=CC=CC=1>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([Cl:26])=[O:23])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1)#[N:2]

Participants

5

Reactant 2

HCID 24386Thionyl ChlorideHCID 199362016-(4'-Cyanobiphenyl-4-oxy)caproic acid

Product 1

HCID 19936198HCID 19936198, compound

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideCatalystHCID 1140TolueneSolvent

Procedure

A solution comprising 16.3 g (52.7 mmol) of 6-(4'-cyanobiphenyl-4-oxy)caproic acid, 7.5 g (63.3 mmol) of thionyl chloride and 3 drops of dimethylformamide in 160 ml of toluene was heated at the boil for 1.5 hours. The readily volatile constituents were removed under reduced pressure at 80° C. and the residue was dried under reduced pressure at room temperature.

Workup

  1. temperaturewas heated at the boil for 1.5 hours
  2. customThe readily volatile constituents were removed under reduced pressure at 80° C.
  3. customthe residue was dried under reduced pressure at room temperature

Sources & evidence

ORD record
ord-1c67c1c4ed9c490c8caec4a49b40e0ac
Source dataset
uspto-grants-1995_05
Patent number
US05417882

Reaction notes

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