Phenethylamine → HCID 18460369, compound

HRID 368228Notes

Reaction equation

HRID 368228 reaction equation
[CH2:1]([NH2:9])[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.Cl[C:11]1[C:12]2[CH:25]=[C:24]([N+:26]([O-:28])=[O:27])[S:23][C:13]=2[N:14]=[C:15]([C:17]2[CH:22]=[N:21][CH:20]=[CH:19][N:18]=2)[N:16]=1>>[N:18]1[CH:19]=[CH:20][N:21]=[CH:22][C:17]=1[C:15]1[N:16]=[C:11]([NH:9][CH2:1][CH2:2][C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)[C:12]2[CH:25]=[C:24]([N+:26]([O-:28])=[O:27])[S:23][C:13]=2[N:14]=1

Participants

3

Reactant 2

HCID 1001PhenethylamineHCID 184601964-Chloro-2-(pyrazin-2-yl)-6-nitro-thieno-[2,3-d]-pyrimidine

Product 1

HCID 18460369HCID 18460369, compound

Procedure

With the procedure of Example 1, the reaction of phenethylamine with 4-chloro-2-(pyrazin-2-yl)-6-nitro-thieno-[2,3-d]-pyrimidine yields 2-(pyrazin-2-yl)-4-phenethylamino-6-nitro-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-51bd7de04299434c8a692c5a3b473e2b
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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