反应详情

温度

80 °C

To 2 ml of N-methylpyrrolidone were added 1.65 g of 2,3,5,6-tetrafluoro-4-methylpyridine and 2.30 g of benzylamine, and the mixture was stirred at 80° C. for 2 hours and allowed to cool. After adding 25 ml of chloroform, the mixture was washed three times with 300 ml of distilled water. The chloroform layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to obtain the title compound in crude form.

1. temperatureto cool
2. washthe mixture was washed three times with 300 ml of distilled water
3. dry with materialThe chloroform layer was dried over anhydrous magnesium sulfate
4. concentrationconcentrated under reduced pressure