HuagongsheHuagongshe Chemistry Print Report · For research reference only
Silane, chloro(chloromethyl)dimethyl- → n,n-Diethyl-2-chloro-6-[(chloromethyl)dimethylsilyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Silane, chloro(chloromethyl)dimethyl- | HCID 74393 | — |
| Reactant | 2-Chloro-N,N-diethylbenzamide | HCID 82566 | — |
| Product | n,n-Diethyl-2-chloro-6-[(chloromethyl)dimethylsilyl]benzamide | HCID 18630016 | — |
Reaction Steps
The title compound was prepared according to General Method A from the compound of Example e and 1.5 eq (chloromethyl)dimethylsilyl chloride. Purification by HPLC using 1:9 ethyl acetate/hexanes gave 5.4 g of the desired compound as a yellow oil, an 85% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133252 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-50db707cf0e149059d1bd51e3d57c7ab |
| Source note | uspto-grants-2000_10 |