反应详情

温度

60 °C

A mixture of crude 5a and pyridinium-p-toluenesulfonate (70 g, 0.278mole) in ethanol (250 ml) is heated at 60° C. for 9 hours. The reaction mixture is concentrated in vacuo and co-evaporated with toluene. The residue is diluted with toluene and the resulting solid is removed by filtration. The filtrate is evaporated under reduced pressure to give the crude 6a as light brown oil.

1. concentrationThe reaction mixture is concentrated in vacuo and co-evaporated with toluene
2. additionThe residue is diluted with toluene
3. customthe resulting solid is removed by filtration
4. customThe filtrate is evaporated under reduced pressure