Butyl iodide → 5-bromo-1-butyl-3-[(1-methylpiperidin-4-yl)thio]1H-indole

HRID 36897Notes

Reaction equation

HRID 36897 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[S:11][CH:12]1[CH2:17][CH2:16][N:15]([CH3:18])[CH2:14][CH2:13]1.I[CH2:20][CH2:21][CH2:22][CH3:23]>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:20][CH2:21][CH2:22][CH3:23])[CH:6]=[C:5]2[S:11][CH:12]1[CH2:17][CH2:16][N:15]([CH3:18])[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 10962Butyl iodideHCID 19936616HCID 19936616, compound

Product 1

HCID 199366435-bromo-1-butyl-3-[(1-methylpiperidin-4-yl)thio]1H-indole

Procedure

Prepared as described in Example 56 by reaction of 5-bromo-3[(1-methylpiperidin-4-yl)thio]-1H-indole (prepared in Example 44) with iodobutane.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d6d03136904b410ca907b60713eb9a64
Source dataset
uspto-grants-1995_05
Patent number
US05418242

Reaction notes

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