Methylamine → HCID 23284794, compound

Participants

Reaction Steps

A 40% aqueous solution (150 mg) of methylamine and 1-(5-amino-2,4-difluorophenyl)-8-bromo-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (150 mg) were added to pyridine (3 ml), and the mixture was stirred at room temperature for 2 hours. After the solvent was distilled off under reduced pressure, a mixed liquid of ethanol and diethyl ether was added to the residue, and solids were collected by filtration to obtain the title compound (40 mg) as a light brown powder.

Provenance & Evidence