Hydrochloric Acid → HCID 23284712, compound

Participants

Reaction Steps

12N Hydrochloric acid (2 ml) was added to ethyl 7-amino-1-(5-tert-butoxycarbonylamino-2,4-difluorophenyl)-6-methoxy-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate, and the mixture was heated under reflux for 3 hours. After the reaction mixture was allowed to cool, solids deposited were collected by filtration, washed successively with water and ethanol and then dried to obtain the title compound (52 mg) as a yellow powder.

Provenance & Evidence