反应详情

To 34.0 g (0.15 mol) of 2,5-dichloro-benzene sulfonamide in 200 mL of DMF was added 16.0 g (0.28 mol) of sodium hydrogensulfide. The mixture was refluxed for 18 hours, then cooled, concentrated, and the solids collected by filtration. The solids were dissolved in hot water, the pH adjusted to 4.0 and the precipitate filtered. This material was dried to yield 10.1 g of the title compound, mp 142°-144° C.

1. temperatureThe mixture was refluxed for 18 hours
2. temperaturecooled
3. concentrationconcentrated
4. filtrationthe solids collected by filtration
5. dissolutionThe solids were dissolved in hot water
6. filtrationthe precipitate filtered
7. customThis material was dried