Triethylamine → HCID 19936569, compound

HRID 36936Notes

Reaction equation

HRID 36936 reaction equation
[Br:1][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[CH:5]=[CH:4][C:3]=1[OH:12].C(N(CC)CC)C.[CH3:20][C:21]1[CH:29]=[CH:28][CH:27]=[CH:26][C:22]=1[C:23](Cl)=[O:24]>ClCCl>[Br:1][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[CH:5]=[CH:4][C:3]=1[O:12][C:23](=[O:24])[C:22]1[CH:26]=[CH:27][CH:28]=[CH:29][C:21]=1[CH3:20]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 702762-Methylbenzoyl chlorideHCID 222787171-Bromo-5,6,7,8-tetrahydro-2-naphthalenol

Product 1

HCID 19936569HCID 19936569, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 1-bromo-5,6,7,8-tetrahydro-2-naphthol (6.81 g) and triethylamine (4.2 ml) in dichloromethane (60 ml) was added 2-methylbenzoyl chloride (4.62 g) dropwise with ice-cooling. The mixture was stirred under ice cooling for 1 hour, after which it was washed with water and dried (MgSO4). The solvent was then distilled off to give 1-bromo-2-(2-methylbenzoyloxy)-5,6,7,8-tetrahydronaphthalene as oil in quantitative yield.

Workup

  1. temperaturecooling
  2. washafter which it was washed with water
  3. dry with materialdried (MgSO4)
  4. distillationThe solvent was then distilled off

Sources & evidence

ORD record
ord-39801a50bfdf4158bd8448de7cfbd829
Source dataset
uspto-grants-1995_05
Patent number
US05418239

Reaction notes

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