HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acrylate → Ethyl 3-(2-ethoxycarbonylethyl)amino-2,2-dimethylbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Reactant | Ethyl 3-amino-2,2-dimethylbutanoate | HCID 23283845 | — |
| Product | Ethyl 3-(2-ethoxycarbonylethyl)amino-2,2-dimethylbutanoate | HCID 23283843 | — |
Reaction Steps
In the second stage of the reaction, the ethyl 3-amino-2,2-dimethylbutanoate derivative 4 is reacted with ethyl acrylate to obtain the corresponding ethyl 3-(2-ethoxycarbonylethyl)amino-2,2-dimethylbutanoate derivative 5--which in the case of the preparation of BIII 277 might be, for example: ethyl 3-(2-ethoxycarbonylethyl)amino-4-(3-methoxyphenyl)-2,2-dimethylbutanoate (R2 =CH3O): ##STR4##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06136980 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-092cb85e747445b1811dd473085e4bf4 |
| Source note | uspto-grants-2000_10 |