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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 36955Generated: October 28, 2026

3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile → HCID 11374697, compound

https://huagongshe.com/reaction/36955

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrileHCID 9865114—
ReactantPyridinium chlorideHCID 10176127—
SolventPyridineHCID 1049—
ProductHCID 11374697HCID 11374697—

Reaction Steps

A mixture of 4.05 g of 3-[4-(4-p-methoxyphenylpiperazino)butyl]-5-cyanoindole, 3.5 g of pyridine hydrochloride and 80 ml of pyridine is boiled for 3 hours. It is cooled, evaporated and worked up in a conventional manner, and 3-[4-(4-p-hydroxyphenylpiperazino)butyl]-5-cyanoindole is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05418237
Source datasetuspto-grants-1995_05
ORD IDord-ecc0daa1958b435ba6e5e0da87fa0b8e
Source noteuspto-grants-1995_05