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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 369716Generated: October 30, 2026

Indoline → 4-(2,3-Dihydroindol-1-yl)-6-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d]-pyrimidine

https://huagongshe.com/reaction/369716

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndolineHCID 10328—
Reactant4-Chloro-6-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidineHCID 23282457—
Product4-(2,3-Dihydroindol-1-yl)-6-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d]-pyrimidineHCID 23282466—

Reaction Steps

This product is prepared in a manner analogous to that described in Example 1 from 4-chloro-6-(4-methoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidine and 2,3-dihydroindole (1.1 equivalents). M.p. >300° C.; FAB-MS: (M+H)+ =343 (corresponds to C21H18N4O).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06140317
Source datasetuspto-grants-2000_10
ORD IDord-cea43a8abcb1415bbbf2ce58c997d3f3
Source noteuspto-grants-2000_10