Triethylamine → 21961-10-4

HRID 369768Notes

Reaction equation

HRID 369768 reaction equation
[CH:1]1([S:7]([CH2:10][CH2:11]O)(=[O:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(N(CC)CC)C.CS(Cl)(=O)=O>C(Cl)Cl>[CH:10]([S:7]([CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)(=[O:8])=[O:9])=[CH2:11]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 23282673HCID 23282673, compound

Product 1

HCID 2197619521961-10-4

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

A solution of 2-cyclohexylsulfonylethanol (22 g) and triethylamine (30 ml) in methylene chloride (200 ml) was treated dropwise with a solution of methanesulfonyl chloride (15 ml) in methylene chloride (100 ml) at 10° C. After stirring for 2 h at room temperature the mixture was washed with water, dried over magnesium sulfate and concentrated in vacuo leaving the product, cyclohexyl vinyl sulfone, as an oil (19 g).

Workup

  1. washwas washed with water
  2. dry with materialdried over magnesium sulfate
  3. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-6ec9b5857ef54490a67a694a0c4909c5
Source dataset
uspto-grants-2000_10
Patent number
US06140331

Reaction notes

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