HRID36979

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CCCCc1ncc(/C(C)=C(\Cc2ccsc2)C(=O)O)n1Cc1ccccc1Cl$

HCID19802812

未命名化合物

结构：CCCC/C(=C(/Cc1cccs1)C(=O)OCC)c1cnc(CCCC)n1COCC[Si](C)(C)C

HCID86748681

未命名化合物

PRODUCTS

生成物

结构：CCCC/C(=C(/Cc1cccs1)C(=O)OCC)c1cnc(CCCC)n1Cc1ccccc1Cl

HCID86748680

未命名化合物

PROCEDURE

实验过程

The procedure of Example 6, Method B (iv, v) is followed using ethyl (E)-3-[2-n-butyl-1-{(trimethylsilyl)ethoxymethyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2heptenoate in in place of ethyl (E)-3-[2-n-butyl-1-{(trimethylsilyl) ethoxymethyl}-1H-imidazol-5-yl]-2-(5-methyl-2-furyl)methyl-2-heptanoate to give the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1f58bf722bd240a89f8dce0f0e006e0c
来源数据集: uspto-grants-1995_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05418250
来源说明: uspto-grants-1995_05

反应 SMILES

C(C1N(C[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=2[Cl:29])C(/C(/C)=C(\CC2C=CSC=2)/C(O)=O)=CN=1)CCC.[CH2:30]([C:34]1[N:35]([CH2:56]OCC[Si](C)(C)C)[C:36](/[C:39](/[CH2:52][CH2:53][CH2:54][CH3:55])=[C:40](\[CH2:46][C:47]2[S:48][CH:49]=[CH:50][CH:51]=2)/[C:41]([O:43][CH2:44][CH3:45])=[O:42])=[CH:37][N:38]=1)[CH2:31][CH2:32][CH3:33]>>[CH2:30]([C:34]1[N:35]([CH2:56][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=2[Cl:29])[C:36](/[C:39](/[CH2:52][CH2:53][CH2:54][CH3:55])=[C:40](\[CH2:46][C:47]2[S:48][CH:49]=[CH:50][CH:51]=2)/[C:41]([O:43][CH2:44][CH3:45])=[O:42])=[CH:37][N:38]=1)[CH2:31][CH2:32][CH3:33]