HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → HCID 178488432, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | Ethyl 2-amino-5-(4-methoxyphenyl)-1H-pyrrole-3-carboxylate | HCID 23282706 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178488432 | HCID 178488432 | — |
Reaction Steps
Under a protective gas, 611 mg (2.3 mmol) of 2-amino-3-ethoxycarbonyl-5-(4-methoxy-phenyl)-1H-pyrrole in 5 ml of formamide, 2.5 ml of DMF and 1.25 ml of formic acid are heated at 150° C. overnight. Working-up analogously to Step 8.2 yields the title compound; m.p.>300° C.; FAB-MS: (M+H)+ =242.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06140332 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-acc756ec38284bed99b573c3fd42a420 |
| Source note | uspto-grants-2000_10 |