2-(1-Pyrrolidinyl)carbonyl-1-benzylpyrrolidine → Pyrrolidin-1-yl(pyrrolidin-2-yl)methanone

Participants

Reaction Steps

In ethanol (300 ml) is suspended 5% palladium-carbon (3 g), and thereto is added 2-(1-pyrrolidinyl)carbonyl-1-benzylpyrrolidine (30 g), and the mixture is subjected to catalytic hydrogenation at room temperature under atmospheric pressure. The mixture is filtered, and the filtrate is concentrated under reduced pressure to remove the solvent to give 2-(1-pyrrolidinyl)carbonylpyrrolidine (about 18 g) as an oily product.

Provenance & Evidence