Ammonium Hydroxide → HCID 15407444, compound

HRID 369932Notes

Reaction equation

HRID 369932 reaction equation
[CH3:1][CH:2]1[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[N:3]1.[N+:12]([O-])([O-:14])=[O:13].[K+].[OH-].[NH4+]>S(=O)(=O)(O)O>[CH3:1][CH:2]1[CH2:11][C:10]2[C:5](=[CH:6][C:7]([N+:12]([O-:14])=[O:13])=[CH:8][CH:9]=2)[CH:4]=[N:3]1

Participants

5

Reactant 3

HCID 14923Ammonium HydroxideHCID 24434Potassium NitrateHCID 152540493,4-Dihydro-3-methylisoquinoline

Product 1

HCID 15407444HCID 15407444, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

3-Methyl-3,4-dihydroisoquinoline (7.0 g, 48.2 mmol) was dissolved in concentrated sulfuric acid (150 ml) and to this was added potassium nitrate (4.9 g, 50.0 mmol). The mixture was allowed to stir overnight, dumped onto ice, and neutralized with the addition of concentrated ammonium hydroxide. The precipated solids were collected by filtration, washed, and air-dried: 7.5 g (82%), m.p. 110-2° C.

Workup

  1. filtrationThe precipated solids were collected by filtration
  2. washwashed
  3. customair-dried

Sources & evidence

ORD record
ord-a313305b6fa949a8b57c445a6c0f0bc6
Source dataset
uspto-grants-2000_10
Patent number
US06140322

Reaction notes

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