huagongshe.com
HRID370452

反应详情

EQUATION

反应方程式

HRID 370452 的结构方程式

REACTANTS

反应物

4
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：ClC1=NCCN1
HCID236236

2-chloro-4,5-dihydro-1H-imidazole

C3H5ClN2

结构：ClC1=NCCN1.O=S(=O)(O)O
HCID12503398

Sulfuric acid--2-chloro-4,5-dihydro-1H-imidazole (1/1)

C3H7ClN2O4S

结构：Cn1cc2c(N)cccc2n1
HCID15413170

2-Methyl-2H-indazol-4-amine

C8H9N3

PRODUCTS

生成物

1
结构：Cl.Cn1cc2c(NC3=NCCN3)cccc2n1
HCID121924

N-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-2H-indazol-4-amine--hydrogen chloride (1/1)

C11H14ClN5

AUXILIARIES

试剂、催化剂与溶剂

2
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

4 g 4-amino-2-methyl-indazole is dissolved in 120 ml THF. The solution is treated with a solution of 2-chloro-imidazoline base, which is prepared from 10 g 2-chloro-imidazoline sulfate (prepared according to J. Heteroc. Chem. 11, 258) with 2n NaOH in methylene chloride.