1-Phenylpiperazine → HCID 13531609, compound

HRID 370473Notes

Reaction equation

HRID 370473 reaction equation
Br[CH2:2][C:3]1[CH:4]=[CH:5][C:6]2[O:10][C:9]([N+:11]([O-:13])=[O:12])=[C:8]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:7]=2[CH:20]=1.[C:21]1([N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>C(O)C>[N+:11]([C:9]1[O:10][C:6]2[CH:5]=[CH:4][C:3]([CH2:2][N:30]3[CH2:31][CH2:32][N:27]([C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)[CH2:28][CH2:29]3)=[CH:20][C:7]=2[C:8]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([O-:13])=[O:12]

Participants

4

Reactant 2

HCID 70961-PhenylpiperazineHCID 13531604HCID 13531604, compound

Product 1

HCID 13531609HCID 13531609, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using the method of Example 1, 5-bromomethyl-2-nitro-3-phenylbenzofuran is reacted with N-phenylpiperazine in ethanol to provide yellow needles of 4-(2-nitro-3-phenyl-5-benzofuranylmethyl)-1-phenylpiperazine, m.p. 155°-157° C., having the structure ##STR12##

Sources & evidence

ORD record
ord-0b05f8064b234c5f8aa0d61d16b2ab5d
Source dataset
uspto-grants-1985_07
Patent number
US04526896

Reaction notes

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