Benzoyl chloride, 3-nitro- → HCID 178522673, compound

HRID 370532Notes

Reaction equation

HRID 370532 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7](Cl)=[O:8])([O-:3])=[O:2].O.[NH2:14][C:15]1[NH:19][N:18]=[N:17][N:16]=1>O1CCCC1.O>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7]([NH:14][C:15]1[NH:19][N:18]=[N:17][N:16]=1)=[O:8])([O-:3])=[O:2]

Participants

5

Reactant 2

HCID 8495Benzoyl chloride, 3-nitro-HCID 178509300HCID 178509300, compound

Product 1

HCID 178522673HCID 178522673, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent2×

Procedure

In a similar manner, a solution of 46.4 g of 3-nitrobenzoyl chloride in 100 ml of tetrahydrofuran was added to a hot solution of 51.6 g of 5-aminotetrazole monohydrate in 1200 ml of tetrahydrofuran and 50 ml of water. The mixture was allowed to stand for 16 hours and then concentrated, and the resulting slurry was treated with water. The white solid was collected, washed with water and oven-dried to give 3-nitro-N-(1H-tetrazol-5-yl)benzamide melting at about 276° C. with decomposition.

Workup

  1. concentrationconcentrated
  2. additionthe resulting slurry was treated with water
  3. customThe white solid was collected
  4. washwashed with water
  5. customoven-dried

Sources & evidence

ORD record
ord-17a32fad7ebb4d17aca53574810e87a5
Source dataset
uspto-grants-1985_07
Patent number
US04526979

Reaction notes

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