HCID 86740187, compound → 4-amino-5-fluoropent-2-enoic acid

Participants

Reaction Steps

410 mg of 26C was stirred in 25 ml of 5N hydrochloric acid for 48 hours at room temperature, then the solvent was evaporated at a temperature below 40° C. and the residue was dried over phosphorus pentoxide for 24 hours. The resulting product was recrystallized from acetic acid/ethyl acetate to give 26, as powdery white flakes, m.p.: 169°-170° C.

Provenance & Evidence