Fumaric Acid → 1H-Imidazole, 1-(1-naphthalenylmethyl)-

HRID 370654ノート

反応式

HRID 370654 の反応式
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[C:9]1([CH2:19][N:20]2[CH:24]=[CH:23][N:22]=[CH:21]2)[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][CH:10]=1>C(O)C>[C:9]1([CH2:19][N:20]2[CH:24]=[CH:23][N:22]=[CH:21]2)[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][CH:10]=1.[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([O-:6])=[O:5]

参加物

5

反応物 2

HCID 444972Fumaric AcidHCID 5882441H-Imidazole, 1-(1-naphthalenylmethyl)-

生成物 2

HCID 5882441H-Imidazole, 1-(1-naphthalenylmethyl)-HCID 6183479Fumarate(1-)

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

A solution of fumaric acid (0.21 g) in hot ethanol (10 ml) was added to a solution of 1-(1-naphthylmethyl)imidazole (0.4 g) in ethanol (5 ml). After boiling for 10 minutes, the solution was evaporated under reduced pressure to afford a white solid. Recrystallisation of the solid from ethanol afforded 1-(1-naphthylmethyl)imidazole, hydrogen fumarate, m.p. 159°-161° C.

後処理

  1. customthe solution was evaporated under reduced pressure
  2. customto afford a white solid
  3. customRecrystallisation of the solid from ethanol

出典と根拠

ORDレコード
ord-e1aa70e85ad849448a0703aeaf4bce23
出典データセット
uspto-grants-1985_07
特許番号
US04528195

反応ノート

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