HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20275376, compound → HCID 20275386, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20275376 | HCID 20275376 | — |
| Reactant | HCID 20275380 | HCID 20275380 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 20275386 | HCID 20275386 | — |
Reaction Steps
Following the procedure of Example 2, but substituting an equivalent amount of methyl 5-(2-acetylthiomethyl-propionamido)-nicotinate, obtained as disclosed in Example 12, for methyl 2-(2-acetylthiomethyl-propionamido)-nicotinate and using a mixture of methylene chloride/methanol 99:1 as eluent for the chromatographic column, methyl 5-(2-mercaptomethyl-propionamido)-nicotinate is obtained: m.p. 96°-97° C., from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04528296 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-42ec96d449c84a6c94b1137f824e2b53 |
| Source note | uspto-grants-1985_07 |