HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-N-(1-methylethyl)benzamide → N-Isopropyl 4-Chlorobenzimidoyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-N-(1-methylethyl)benzamide | HCID 24045 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | N-Isopropyl 4-Chlorobenzimidoyl Chloride | HCID 12582456 | — |
Reaction Steps
N-Isopropyl 4-chlorobenzamide (12.7 g, 64.3 mmole) and thionyl chloride (53.81 g, 447 mmole) were heated at reflux with stirring for two hours. Excess thionyl chloride was removed by distillation. The title compound was isolated by distillation (b.p. 65°-70° C. at ~1 mm Hg) to yield 10.7 g (77%) of a light brown yellow liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04528382 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-b2a44d9e97fb44039cf3f9aabac53208 |
| Source note | uspto-grants-1985_07 |