反应详情

N-Octyl 4-chlorobenzamide (17.2 g, 64.2 mmole) and thionyl chloride (42.59 g, 358 mmole) were stirred and heated at reflux for one hour. The product was isolated by fractional distillation at reduced pressure (b.p. 70°-90° C. at 15 mm Hg) to yield 14.0 g (77%) of impure title compound.

1. temperatureheated
2. temperatureat reflux for one hour
3. customThe product was isolated by fractional distillation at reduced pressure (b.p. 70°-90° C. at 15 mm Hg)