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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 371130Generated: October 31, 2026

3-(Trifluoromethyl)aniline → 1-Methyl-3-[3-(trifluoromethyl)phenyl]-1H-pyrrole-2,5-dione

https://huagongshe.com/reaction/371130

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)anilineHCID 7375—
ReactantN-MethylmaleimideHCID 70261—
Product1-Methyl-3-[3-(trifluoromethyl)phenyl]-1H-pyrrole-2,5-dioneHCID 20274406—

Reaction Steps

An 80.6 g portion of 3-aminobenzotrifluoride was reacted with 55.6 g of N-methylmaleimide as described in Example 6, giving 2-(m-trifluoromethylphenyl)-N-methylmaleimide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04529736
Source datasetuspto-grants-1985_07
ORD IDord-4d55922743f24e3a8745ea3750ec8fc2
Source noteuspto-grants-1985_07