Hydrochloric Acid → HCID 14346472, compound

HRID 371223Notes

Reaction equation

HRID 371223 reaction equation
[O:1]=[C:2]1[C@@H:5]([NH:6][C:7](=[O:26])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[CH2:14][NH:15]C(OCC2C=CC=CC=2)=O)[CH2:4][N:3]1[S:27]([OH:30])(=[O:29])=[O:28].[K].[H][H].Cl>[Pd]>[NH2:15][CH2:14][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=1[C:7]([NH:6][C@H:5]1[CH2:4][N:3]([S:27]([OH:30])(=[O:28])=[O:29])[C:2]1=[O:1])=[O:26]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 5462222PotassiumHCID 13575263HCID 13575263, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 14346472HCID 14346472, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The deprotection of (S)-2-oxo-3-[[2-[[[(phenylmethoxy)carbonyl]amino]methyl]benzoyl]amino]-1-azetidinesulfonic acid, potassium salt (see example 167) using hydrogen gas, palladium on charcoal, and hydrochloric acid, yields the title compound, melting point 162°-165° C.

Sources & evidence

ORD record
ord-56ae5c30a82646a2b3bff23dd36831f5
Source dataset
uspto-grants-1985_07
Patent number
US04529698

Reaction notes

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